World Diabetes Day 14.11.2017

November 14th, 2017 | Posted By: Clare Panchoo | Posted in News | Tagged , , , , , , , ,

Today is World Diabetes Day

  • The number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014
  • In 2015, an estimated 1.6 million deaths were directly caused by diabetes.
  • Another 2.2 million deaths were attributable to high blood glucose in 2012.
  • Over the past 30 years, the number of people with diabetes in the US has quadrupled, and it has been predicted that this could increase to as many as one in every three adults by 2050
  • Up to 70% of cases of type 2 diabetes could be prevented through the adoption of a healthy lifestyle
Source: www.idf.org

Veri-te™ Resveratrol & Diabetes

There are over 500 published studies, including multiple clinical trials, that investigate the effects of resveratrol on blood glucose control and metabolism.

 

Clinical studies show that resveratrol:
  • Helps control blood glucose levels
  • May improve insulin sensitivity
  • May reduce risk factors in prediabetes
  • Possesses an excellent safety profile and no observed drug interactions

 

References:
  1. US Centers for Disease Control and Prevention. Diabetes 2014 report card. Available
    from: www.cdc.gov/diabetes/library/reports/congress.html. Accessed September 2015.
  2. Agarwal B and Baur JA. Resveratrol and life extension. Ann N Y Acad Sci 2011;1215:
    138-143.
  3. Lagouge M, Argman C, Gerhart-Hines Z, et al. Resveratrol improves mitochondrial
    function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
    Cell 2006;127(6):1109-1122.
  4. Sun C, Zhang F, Ge X, et al. SIRT1 improves insulin sensitivity under insulin-resistant
    conditions by repressing PTP1B. Cell Metab 2007;6(4):307-319.
  5. Timmers S, Konings E, Bilet L, et al. Calorie restriction-like effects of 30 days of resveratrol
    supplementation on energy metabolism and metabolic profile in obese humans.
    Cell Metab 2011;14(5): 612-622.
  6. Yun JM, Chien A, Jialal I and Devaraj S. Resveratrol up-regulates SIRT1 and inhibits
    cellular oxidative stress in the diabetic milieu: mechanistic insights. J Nutr Biochem
    2012;23(7):699-705.
  7. Farimani AR, Saidijam M, Goodarzi MT, et al. Effect of Resveratrol Supplementation on
    the SNARE Proteins Expression in Adipose Tissue of Stroptozotocin-Nicotinamide
    Induced Type 2 Diabetic Rats. Iran J Med Sci 2015;40(3):248-255.
  8. Sun L, Wang Y, Song Y, et al. Resveratrol restores the circadian rhythmic disorder of
    lipid metabolism induced by high-fat diet in mice. Biochem Biophys Res Comm
    2015;458:86-91.
  9. Bhatt JK, Thomas S and Nanjan MJ. Resveratrol supplementation improves glycemic
    control in type 2 diabetes mellitus. Nutr Res 2012;32:53-541.
  10. Movahed A, Nabipour I, Lieben Louis X, et al. Antihyperglycemic effects of short term
    resveratrol supplementation in type 2 diabetic patients. Evid Based Complement
    Alternat Med 2013; Article ID 851267,2013. doi:10.1155/2013/851267.
  11. Brasnyo P, Molnar BA, Mohas M, et al. Resveratrol improves insulin sensitivity,
    reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.
    Br J Nutr 2011;106(3):383-389.
  12. Crandall JP, Oram V, Trandafirescu G, et al. Pilot study of resveratrol in older adults with
    impaired glucose tolerance. J Gerontol A Biol Sci Med Sci 2012;67(12):1307-1312.
  13. Liu K, Zhou R, Wang B and Mi M-T. Effect of resveratrol on glucose control and
    insulin sensitivity: a meta-analysis of 11 randomized controlled trials. Am J Clin Nutr
    2014;99(6):1510-1519.